Custom Peptides
Cayman Chemical TIplaxtInIn 10mg
A PAI-1 inhibitor (IC50 = 2.7 µM for the human enzyme); inhibits differentiation of human adipocytes at 5 µM; reduces tumor growth and microvessel density in a T24 bladder cancer mouse xenograft model at 5 and 20 mg/kg; prevents carotid artery occlusion, increases the time to occlusive thrombosis, and decreases the thrombus size in a rat model of ferric chloride-induced arterial thrombosis at 1 mg/kg
Cayman Chemical CarotenoId MIxture 10mg
A mixture of carotenoids; contains capsanthin and β-carotene, as well as additional carotenoids and carotenoid esters
Cayman Chemical 2-O-MethyladenosIn 10mg
An analog of adenosine used to prepare nucleoside derivatives as inhibitors of viral RNA translation and replication
Cayman Chemical JWH398 5CLORNaphthyl Isom 10mg
An analytical reference standard that is structurally similar to known synthetic cannabinoids; intended for research and forensic applications
Cayman Chemical SB-269970hydrochlorIde 10mg
A potent 5-HT7A antagonist (pKi = 8.9) that demonstrates >50-fold binding selectivity over 5-HT5A and >250-fold selectivity over 5-HT1, 5-HT2, 5-HT4, 5-HT6, adrenergic α1, dopamine D2, and dopamine D3 receptors
Cayman Chemical HypophylnthIn 10mg
An active principle of P. amarus that has been shown to reversibly inhibit P-glycoprotein (also known as multidrug resistance protein 1 (MDR1)) function without effect on MDR2 activity
Cayman Chemical 4MethyLMbelIferylNacetyl 10mg
A fluorogenic substrate of neuraminidases; cleaved by neuraminidases to release the fluorescent moiety 4-MU; has been used to quantify neuraminidase activity in mammalian cells and clinical isolates of influenza virus
Cayman Chemical PIcropodophylotoxIn 10mg
A potent and selective inhibitor of IGF-1R (IC50 = 6 nM) causes cell cycle arrest and induces apoptosis in cancer cells both in vitro and in vivo
Cayman Chemical 3DeoxyDglyceroDgalacto2 10mg
A naturally occuring deaminated sialic acid that is thought to be a precursor for the biosynthesis of other members of the sialic acid family; can be used to analyze nonulosonic acid residues in polysialoglycoproteins
Cayman Chemical ZatebradInhydrochlorIde 10mg
Blocks If currents through HCN channels in sinoatrial node cells (IC50s = 1.83, 2.21, 1.9, and 1.88 µM, respectively for HCN1-4 in vitro); reduces heart rate from 600 to 200 beats per minute with an ED50 value of 1.8 mg/kg and induces increasing arrhythmia at concentrations >10 mg/kg when assessed through telemetric ECG recording in mice
Cayman Chemical IsoxnthopterIn 10mg
A natural intermediate in the pteridine pathway that can be produced naturally from 7-oxobiopterin or in vitro by the oxidation of pterin by xanthine oxidase
Cayman Chemical PerhexIlInmaleate 10mg
A CPT1 and CPT2 inhibitor that inhibits rat heart and liver CPT1 (IC50 = 77 and 148 µM, respectively), and rat heart CPT2 (IC50 = 79 µM); inhibits mTORC1 signaling and induces autophagy in MCF-7 cells at low µM levels
Cayman Chemical 15 S-Latnoprost 10mg
A 15(S) isomer of latanoprost; reduces IOP in cynomolgus monkeys and does not induce eye irritation in cats when applied topically at 3 UG/eye; a potential impurity in commercial preparations of latanoprost
Cayman Chemical 2MethylamIno1phenylbutn 10mg
A methamphetamine analog with structural similarity to 2-ethylamino-1-phenylbutane; intended for forensic and research applications